Leverage | What is Mesotherapy
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What is Mesotherapy

Aging is a complex, multifactorial process that affects every organ in the body, including the skin.Clinically, aged skin is characterized as thin, dry, and pale, with noticeable wrinkles and decreased elasticity.The histological changes associated with aging in skin include the accumulation of elastotic material in the papillary and mid-dermis, a process known as solar elastosis, and quantitative changes in collagen, which are reflected in a decline in biosynthesis and content.

Mesotherapy, initially described in France by Michel Pistor, is one of the modalities recently used to rejuvenate and tone the skin.It involves the non-invasive transdermal injection of vitamins, enzymes, hormones, hyaluronic acid, and natural plant extracts into the skin to stimulate the biosynthetic ability of fibroblasts and facilitate interaction between cells and is intended to increase collagen and elastin production. Different injection techniques can be used in mesotherapy: (i) the intra-epidermal technique; (ii) the papular technique, in which reagents are injected into the dermo–epidermal junction; (ii) the nappage method, in which injections penetrate to a depth of 2–4 mm and are delivered at an angle of 30–60°; and (iv) point-by-point injection into the deep dermis.1011